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Compounds such as EGCG and apigenin promote apoptosis in melanoma cells by modulating pathways like MAPK and PI3K-AKT, while green tea polyphenols inhibit histone deacetylase (HDAC) and activate histone acetyltransferase (HAT), reactivating tumor-suppressor genes silenced during melanoma progression 138,148

The key point is that the pancreas falls clinical victim while liver injury is generally silent - but why

Mol Pharmacol 90:288299

These products can be measured via enzyme-linked immunosorbent assay (ELISA), gas chromatography mass spectrometry (GC-MS) or by liquid chromatography- mass spectrometry (LC-MS) (35)

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